Generation of an OCT3/4 reporter cynomolgus monkey ES cell line using CRISPR/Cas9
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چکیده
منابع مشابه
Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos
Monkeys serve as important model species for studying human diseases and developing therapeutic strategies, yet the application of monkeys in biomedical researches has been significantly hindered by the difficulties in producing animals genetically modified at the desired target sites. Here, we first applied the CRISPR/Cas9 system, a versatile tool for editing the genes of different organisms, ...
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ژورنال
عنوان ژورنال: Stem Cell Research
سال: 2019
ISSN: 1873-5061
DOI: 10.1016/j.scr.2019.101439